Side-by-side comparisons

Eight organ-on-chip platforms against throughput, perfusion mechanism, membrane versus scaffold-free architecture, imaging compatibility, open versus closed consumables and published tissue models. No vendor publishes consumable pricing, that column is honestly empty.

Three culture architectures compared on physiological relevance, cost per data point, throughput and hands-on time, including an explicit account of when a Transwell insert is the right and cheaper answer, which is more often than the field admits.

A comparison matrix of 3D skeletal muscle models, Curi Bio Mantarray, eNUVIO OMEGA-MP, Duke myobundles, myriamed myrPlate and myrTissue-Skeletal, and CYTOO MyoScreen, on cell source, device, force readout, maturation time, throughput and cost per data point, with published force figures.

A comparison of fourteen 3D tissue model suppliers, MatTek, EPISKIN, InSphero, MIMETAS, Emulate, CN Bio, TissUse, Altis, Visikol, Xellar, Phenion, J-TEC, myriamed and eNUVIO, on tissue types, format, whether they ship finished tissue or an empty device, custom capability and published price band.

A head-to-head of cell banking providers, WiCell, Cook MyoSite, uBriGene, Curi Bio and named institutional cores, on published price, what is included in the release panel, grade, turnaround, deposit-for-distribution options and who owns the resulting bank.

A head-to-head of contract iPSC differentiation providers, Curi Bio, Ncardia, Axol, bit.bio, Cook MyoSite, eNUVIO and FUJIFILM CDI, on lineages, whose line they will work on, published acceptance criteria, timelines, engagement models and the question that decides the purchase: whether the deliverable is cells or a report.

A head-to-head of the validated reconstructed human epidermis models, barrier function and ET-50 acceptance ranges, protocol parameters, OECD TG 439 and TG 431 validation status, formats, lead time and what is actually published about price.

An even-handed head-to-head of human iPSC-derived astrocyte suppliers, price per million, published functional evidence, co-culture protocol support, disease panels, isogenic partners and licence posture, with the co-culture ratio the literature actually used and a note on where primary astrocytes still win.

A head-to-head of the main human iPSC-derived neuron suppliers, price per million, purity specification, subtype breadth, line provenance, published electrophysiology, licensing and minimum order, with a clear statement of where each one is strongest.

A head-to-head of human liver model suppliers, InSphero 3D InSight, MatTek HUREL micro livers, CN Bio PhysioMimix perfused plates, HepaRG and bit.bio ioHepatocytes, on model architecture, donor pooling, longevity, format, published price and what each route actually costs per data point.

A head-to-head of the five multielectrode array platform families, Axion Maestro, MaxWell MaxOne and MaxTwo, Multi Channel Systems, 3Brain CorePlate and Alpha MED MED64, on electrodes per well, simultaneous recording channels, plate reuse, published cell-product protocol support and the per-well economics no vendor will publish.

A head-to-head of named microfluidic fabricators, HiComp, Parallel Fluidics, eNUVIO, FlowJEM, Blue BioDevice, uFluidix, microfluidic ChipShop, Potomac Photonics, ALine and an academic cleanroom, on fabrication method, material, minimum feature size, published tolerances, minimum order quantity, non-recurring engineering cost and who keeps the tooling.

A head-to-head of the three routes to human myogenic progenitors, primary from Cook MyoSite, PromoCell and Lonza, iPSC-derived from iXCells, bit.bio and myriamed, and immortalised lines, on price per million, purity marker, passage window, donor authenticity, disease panels and what each route costs you scientifically.