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Catalogue 66

Entry Class
Human iPSC-Derived Cortical Neurons

Cryopreserved human iPSC-derived cortical neurons, glutamatergic or GABAergic, shipped by vial.

Human & iPSC-Derived Cells WW-CL-56748
Human iPSC-Derived Spinal Motor Neurons

Cryopreserved human iPSC-derived spinal motor neurons, including ALS patient and isogenic control lines.

Human & iPSC-Derived Cells WW-CL-27986
Human iPSC-Derived Neural Stem Cells / NPCs

Expandable human iPSC-derived neural stem cells for customers who want to differentiate in-house.

Human & iPSC-Derived Cells WW-CL-99941
Human iPSC-Derived Astrocytes

Cryopreserved human iPSC-derived astrocytes for neuronal co-culture and glial studies.

Human & iPSC-Derived Cells WW-CL-53875
Human iPSC-Derived Cardiomyocytes

Cryopreserved human iPSC-derived ventricular or atrial cardiomyocytes, spontaneously contractile after plating.

Human & iPSC-Derived Cells WW-CL-42149
Human Skeletal Myoblasts (iPSC-Derived and Primary)

Myogenic progenitor cells for casting skeletal muscle tissue, from iPSC-derived catalog vials up to GMP-grade primary production.

Human & iPSC-Derived Cells WW-CL-69946
Human iPSC Lines

Undifferentiated human induced pluripotent stem cell lines as a starting material for customer-run differentiation.

Human & iPSC-Derived Cells WW-CL-84697
Human iPSC-Derived Microglia

Cryopreserved human iPSC-derived microglia, including APOE and TREM2 disease backgrounds and CRISPR-ready lines.

Human & iPSC-Derived Cells WW-CL-14523
Human iPSC-Derived Oligodendrocytes & OPCs

Cryopreserved human iPSC-derived oligodendrocyte-like cells and oligodendrocyte precursor cells, from the one supplier that publishes a price.

Human & iPSC-Derived Cells WW-CL-27583
Human Vascular Endothelial Cells (HUVEC and Microvascular)

Primary human endothelial cells, pooled or single-donor, with published passage and population-doubling guarantees.

Human & iPSC-Derived Cells WW-CL-49049
Human Hepatocytes (Primary, iPSC-Derived and Cell Line)

Hepatocytes as cells rather than as a finished model, across primary, iPSC-derived and immortalised routes.

Human & iPSC-Derived Cells WW-CL-61619
Human Dermal Fibroblasts & Keratinocytes

The two cell types every skin model is built from, with age grade and disease state selectable at order.

Human & iPSC-Derived Cells WW-CL-75339
Disease-Model & Isogenic iPSC Line Pairs

Matched mutant and corrected iPSC lines from the public banks, priced at both academic and commercial tiers.

Human & iPSC-Derived Cells WW-CL-16632
Rodent & Immortalised Cell Lines for Method Development

The cheap vials that should carry protocol rehearsal, so the expensive human vials carry the experiment.

Human & iPSC-Derived Cells WW-CL-61103
Reconstructed Human Epidermis (Living 3D Skin Tissue)

Living, metabolically active 3D human epidermal tissue on culture inserts, delivered on a weekly production cadence.

Ready-to-Use 3D Tissue Models WW-TM-42266
Reconstructed Human Airway Epithelium

Living pseudostratified, ciliated human airway tissue cultured at an air-liquid interface.

Ready-to-Use 3D Tissue Models WW-TM-87900
Human Intestinal Epithelial Tissue & Barrier Models

Living human small intestine or colon epithelium in planar or crypt format for permeability, metabolism and barrier work.

Ready-to-Use 3D Tissue Models WW-TM-33370
Ready-to-Use Human Liver Microtissues & Spheroids

Pre-formed 3D human liver spheroids delivered ready for dosing, on a published production schedule.

Ready-to-Use 3D Tissue Models WW-TM-25073
Pre-Seeded Perfused Organ-on-Chip Tissue Plates

Microfluidic plates arriving with tissue already seeded and perfused, so the buyer never handles cells or ECM.

Ready-to-Use 3D Tissue Models WW-TM-40272
Reconstructed Human Cornea-Like Epithelium (Ocular Models)

The four corneal models named in OECD TG 492, each with a different published pass mark and batch release range.

Ready-to-Use 3D Tissue Models WW-TM-22013
Oral, Gingival & Mucosal Tissue Models

Buccal, gingival, oesophageal, bladder and vaginal epithelium from the two skin-model suppliers, almost all outside the guideline system.

Ready-to-Use 3D Tissue Models WW-TM-94360
Full-Thickness Human Skin Models (Dermis Plus Epidermis)

Dermal-epidermal skin equivalents, and the only category in this market with a complete published price list.

Ready-to-Use 3D Tissue Models WW-TM-50880
Perfusable Vascular & Microvessel Models

Pre-formed endothelial tubules and angiogenic sprouting models, including the rare assay-ready plate with a public price.

Ready-to-Use 3D Tissue Models WW-TM-79629
Patient-Derived & iPSC-Derived Organoids

Organoid models where the purchase and the permission are two separate transactions, and only one of them has a price.

Ready-to-Use 3D Tissue Models WW-TM-18882
Air-Liquid Interface Bronchial & Nasal Airway Tissue

Ready-to-use pseudostratified, ciliated, mucus-producing human airway epithelium on inserts, specified by anatomical region and donor pathology.

Ready-to-Use 3D Tissue Models WW-TM-68053
Alveolar & Deep-Lung Tissue Models (Static and Perfused)

AT1/AT2 alveolar epithelium with surfactant secretion, available as a static insert tissue or as a perfused microphysiological system on an instrument.

Ready-to-Use 3D Tissue Models WW-TM-22855
Kidney Proximal Tubule & Renal Barrier Models

Perfusable or insert-based human renal proximal tubule epithelium for transporter, permeability and nephrotoxicity work, assembled from publicly priced primary cells.

Ready-to-Use 3D Tissue Models WW-TM-34027
Ready-to-Use Human Cardiac Microtissues & Spheroids

Pre-formed 3D human cardiac microtissues delivered ready for dosing, for contractility, structural and metabolic cardiotoxicity endpoints without an anchored geometry.

Ready-to-Use 3D Tissue Models WW-TM-98451
Tumour Spheroids & 3D Cancer Models

Multicellular tumour spheroids and 3D cancer constructs, where the plasticware and the cell lines are publicly priced and the finished model is not.

Ready-to-Use 3D Tissue Models WW-TM-90207
Blood-Brain Barrier Models (Perfusable and Static)

Perfusable human brain endothelial tubules and static BBB co-cultures for permeability, transporter and CNS penetration work, with one route carrying a live public price.

Ready-to-Use 3D Tissue Models WW-TM-77577
Engineered Contractile Skeletal Muscle Tissue (Built to Spec)

Aligned, mechanically anchored, electrically stimulable engineered skeletal muscle tissue built and force-tested against a written specification.

Engineered Contractile Tissue WW-CT-20881
Neuromuscular Junction Co-Culture Model

Motor neurons and myotubes co-cultured in a compartmentalised device so that neural stimulation drives muscle contraction.

Engineered Contractile Tissue WW-CT-72587
Engineered Heart Tissue (Finished, Anchored, Living)

Finished human engineered myocardium from iPSC-derived cardiomyocytes and fibroblasts, shipped living at ambient temperature with a certificate of analysis, at a published per-tissue price.

Engineered Contractile Tissue WW-CT-71963
Cardiac Microtissue on Flexible Posts (Force-Readable Format)

Cardiomyocytes cast between two flexible posts or stretchers so that contraction deflects a known geometry and force becomes measurable, sold as plate plus cells rather than as finished tissue.

Engineered Contractile Tissue WW-CT-70219
Optogenetic Muscle Construct (Light-Addressable Contractile Tissue)

Engineered muscle carrying a channelrhodopsin so that contraction is triggered by patterned light rather than a field electrode, giving spatial addressing no electrode pair can provide.

Engineered Contractile Tissue WW-CT-93467
MEA-Ready Neural Cultures (Plated, Matured, Delivered Active)

Human neurons plated onto multi-electrode arrays, matured to spontaneous network activity, and delivered as a live recording-ready culture.

Neural Cultures & Electrode Interfaces WW-NI-35246
MEA-Plated Cortical Network (Priced Line by Line)

Human iPSC-derived cortical neurons plated with glia onto a multielectrode array and matured to recordable network activity, costed from a published academic core rate card.

Neural Cultures & Electrode Interfaces WW-NI-14639
Brain Organoid on a Multielectrode Array

A 3D neural organoid coupled to an electrode array so that network activity inside the tissue, not just at its base, becomes recordable.

Neural Cultures & Electrode Interfaces WW-NI-80303
High-Density MEA-Plated Culture (Thousands of Electrodes per Well)

Neuronal or cardiac cultures plated onto CMOS high-density arrays giving thousands of bidirectional electrodes per well, for single-cell-resolution network structure rather than well-average activity.

Neural Cultures & Electrode Interfaces WW-NI-39204
Custom Microfluidic & Culture Device Fabrication

Ground-up design, prototyping and cleanroom production of custom PDMS culture devices, from single prototypes to batch runs.

Culture Devices & Custom Microfabrication WW-DV-73055
3D Skeletal Muscle Casting Devices & Plates

Off-the-shelf micropillar casting devices in which the customer forms their own anchored 3D muscle tissue.

Culture Devices & Custom Microfabrication WW-DV-26263
Tissue Stimulation & Contractile Readout Hardware

Electrical pacing lids and contractile-force measurement instruments for maturing and phenotyping engineered tissue.

Culture Devices & Custom Microfabrication WW-DV-35860
Multielectrode Array Plates & Recording Arrays

MEA consumables sourced to your platform, Axion CytoView multiwell plates, Multi Channel Systems glass arrays, MaxWell HD-MEA plates, with the recurring cost stated before you commit.

Culture Devices & Custom Microfabrication WW-DV-96636
Spheroid & Organoid Microwell Plates

Microwell and ultra-low-attachment plates for aggregate formation, InSphero Akura and Gri3D at published prices, plus the bulk formats that are quote-only.

Culture Devices & Custom Microfabrication WW-DV-22907
Transwell Inserts & Permeable Supports

Permeable membrane inserts specified by material, pore size and pore density rather than by catalogue habit, with published growth areas so your TEER and permeability numbers normalise correctly.

Culture Devices & Custom Microfabrication WW-DV-62498
Perfusion & Flow Control Hardware

Pressure-driven pumps, fluidic units and channel slides for defined shear stress, with the published coefficients that tell you what your flow rate actually means.

Culture Devices & Custom Microfabrication WW-DV-91173
Organ-on-Chip Plates & Chip Consumables

Perfusable chip plates sourced on a per-chip basis, AIM Biotech idenTx and organiX at published list prices, MIMETAS OrganoPlate and Emulate chip kits against derived procurement anchors.

Culture Devices & Custom Microfabrication WW-DV-73744
SU-8 Masters & Priced PDMS Chip Fabrication

Soft-lithography fabrication broken into the two numbers every quote contains, one-time tooling and per-part cost, using the handful of fabricators that publish a rate card.

Culture Devices & Custom Microfabrication WW-DV-22185
3D-Printed Culture Device Prototyping

Resin-printed chambers, manifolds, holders and casting moulds for fast iteration, specified around the two ways printing actually fails.

Culture Devices & Custom Microfabrication WW-DV-79044
Native Animal Tissue Collected to Specification

Tendon, ligament, cartilage and other animal tissues collected, processed and shipped to a written customer specification.

Native & Primary Tissue to Spec WW-NT-87430
Human Biospecimens & Primary Tissue Procurement

Consented human tissue, adipose, biofluids and disease-state specimens sourced from banked inventory or collected prospectively.

Native & Primary Tissue to Spec WW-NT-83139
Human Blood, Leukopaks & Apheresis Products

PBMCs, leukopaks and isolated immune subsets from apheresis donors, including recallable donor programmes.

Native & Primary Tissue to Spec WW-NT-24700
Matched Multi-Sample-Type Material From One Donor

Several cell types, tissues and nucleic acids from the same individual, ordered as a set rather than assembled by luck.

Native & Primary Tissue to Spec WW-NT-11191
Contract Cell Expansion, Banking & Cryopreservation

Outsourced expansion of your cells to a target cell number, cryopreserved into a documented bank at research or GMP grade.

Contract Cell Culture & Manufacturing WW-CC-22056
Contract Differentiation to a Target Cell Type

Outsourced directed differentiation of iPSCs or progenitors into a specified mature cell type, delivered as cells or as a formed tissue.

Contract Cell Culture & Manufacturing WW-CC-60362
iPSC Reprogramming & Line Derivation

Contract reprogramming of fibroblasts, PBMCs or renal epithelial cells into clonal iPSC lines with banked vials and identity testing, one of the few contract services with published prices.

Contract Cell Culture & Manufacturing WW-CC-89677
Research-Grade Cell Banking & Cryogenic Storage

Banking a line you already have, expand, freeze, test and store, at published institutional rates, priced per vial rather than per programme.

Contract Cell Culture & Manufacturing WW-CC-61264
Assay-Ready Cell Plating & Single-Lot Assay Banks

Cells delivered plated, or a single-lot bank aliquoted for a whole campaign, separating the three different products sold under one phrase.

Contract Cell Culture & Manufacturing WW-CC-24070
QC Panel: Sterility, Mycoplasma, Endotoxin, Identity & Viability

Independent release testing of cells or tissue against compendial methods before you accept delivery.

QC, Characterization & Acceptance Testing WW-QC-62912
Histology, Imaging & Digital Pathology Characterization

Sectioning, staining, multiplexed immunofluorescence, 3D imaging and quantitative image analysis of delivered tissue.

QC, Characterization & Acceptance Testing WW-QC-80939
Contractile Force & Electrophysiology Phenotyping

Functional acceptance testing of engineered tissue, twitch and tetanic force, fatigue, damage, and electrophysiological activity.

QC, Characterization & Acceptance Testing WW-QC-30903
STR Identity Profiling & Karyotype Authentication

Independent cell line authentication by STR profiling and G-band karyotype, at published rates, with the loci and database comparison specified rather than assumed.

QC, Characterization & Acceptance Testing WW-QC-73442
Mycoplasma, Sterility & Endotoxin Testing

Contamination and compendial release testing at published rates, with the method stated, because two assays with the same name are not the same test.

QC, Characterization & Acceptance Testing WW-QC-86360
Electrophysiology Characterisation as a Service (MEA Recording)

Buy the recording rather than the platform, MEA recordings and high-content imaging at a published per-recording rate card, with no instrument purchase.

QC, Characterization & Acceptance Testing WW-QC-56610
Cold Chain & Cryogenic Shipping

Packaging, documentation and time-critical shipping of live tissue on cold packs or frozen material on dry ice or in vapour-phase nitrogen.

Cold Chain & Cryo Logistics WW-LG-91414
Validated Cryogenic Shipping & Dry Shipper Hire

Liquid nitrogen vapour shippers rented at published monthly rates, charged and data-logged, for material that cannot travel on dry ice.

Cold Chain & Cryo Logistics WW-LG-66954

Price analysis 14

Entry Type
The master price index

Every verified public price on this site in one table, with the source and the date observed for each. Cells, tissue, plates, chips, QC, banking, devices, shipping and core-facility rates, plus an honest register of what is quote-only and why.

Section index
Academic versus commercial pricing: who qualifies and what it is worth

The published two- and three-tier pricing structures in the engineered living components market, Coriell, Addgene, MD Anderson, Salk, Boston Children's, Baylor, Arizona Genetics Core, with the measured multipliers, who qualifies for each tier, and what the cheap tier does not include.

Price analysis
Buy or differentiate? A cost model for iPSC neurons

A transparent total-cost-of-ownership model for making iPSC-derived neurons in-house versus buying them: reagents, media, line licence, technician hours, facility charge, failure rate and QC, against catalogue price, with breakeven by batches per year. Every unit price is sourced and dated.

Price analysis
Reconstructed human epidermis: what it costs and what you get

A specification and price comparison of reconstructed human epidermis models, MatTek EpiDerm, EPISKIN SkinEthic RHE, Phenion FT and others, with OECD validation status, kit format, shipping cadence and shelf life, and which suppliers publish a price.

Price analysis
The cost of a failed batch

A transparent model of what a failed differentiation costs in cells, consumables, labour, instrument time and schedule, with every unit price sourced and dated, every assumption stated, and the arithmetic shown in full. Explicitly a model, not a quotation.

Price analysis
What an organ-on-chip programme actually costs

Instrument, consumable and per-well economics for organ-on-chip platforms, Emulate, MIMETAS, CN Bio, AIM Biotech and InSphero, built from live storefront prices where they exist and from federal procurement records with stated quantities where they do not.

Price analysis
What astrocytes, microglia and other glia actually cost

Published list prices for human iPSC-derived astrocytes, microglia, oligodendrocytes and OPCs, plus rodent astrocytes, normalised per million cells across iXCells, Axol, bit.bio and FUJIFILM CDI, with the media costs that come attached and the SKUs that are quote-only.

Price analysis
What cell banking actually costs

What master cell banks, working cell banks and research-use banks cost, what testing is bundled into each, and where the published prices stop and the quote-only wall begins. Sourced and dated figures from named providers and published institutional rate cards.

Price analysis
What cell QC testing costs

Published prices for cell line authentication (STR), mycoplasma detection, sterility, karyotyping and endotoxin testing, by assay, method, provider, price and turnaround, with a note on when each test becomes required rather than optional.

Price analysis
What custom microfluidic device fabrication costs

Published fabrication pricing for custom microfluidic and culture devices, split into non-recurring tooling and per-part cost, by method (soft lithography, injection moulding, laser, 3D printing) across volume tiers of 1, 10, 100 and 1,000 parts. Every figure sourced and dated.

Price analysis
What iPSC-derived cardiomyocytes actually cost

Published list prices for human iPSC-derived cardiomyocytes from Axol Bioscience, BPS Bioscience and FUJIFILM Cellular Dynamics, normalised per million cells, with purity specifications and the source and date for every figure.

Price analysis
What iPSC-derived neurons actually cost per million cells

Published list prices for human iPSC-derived neurons, normalised to cost per million cells, across named suppliers. Recorded from supplier sources with the date and URL for each figure.

Price analysis
What it costs to ship living and frozen biological material

Published carrier dangerous-goods surcharges, dry shipper rental rates, supplier handling fees and repository shipping charges for cells and tissue, with what actually drives the number: temperature class, destination, permits and the value of what is inside the box.

Price analysis
What MEA plates and consumables actually cost

No multielectrode array vendor publishes plate pricing. This page derives per-plate costs from US federal procurement records with stated quantities, a published European order confirmation, and live storefront prices for adjacent consumables, with the per-well and per-experiment arithmetic.

Price analysis

Sourcing 22

Entry Type
Sourcing cells, tissue and devices

What Wetware World brokers, how long each category actually takes, and which categories have a catalogue price versus which require an RFQ. A category matrix built from verified supplier data.

Section index
3D muscle culture devices: posts, pillars, plates and what they cost

eNUVIO OMEGA-MP is USD $440.00 for four devices and eight experiments, the only public price in the category. This compares it against OMEGA96-MP, the Curi Bio Mantarray plate kits and custom PDMS posts on well count, post stiffness, force readout and tissue volume.

Price analysis
Buying liver microtissues and spheroids: what ships, what it costs, and when

A sourcing guide to ready-to-use human liver microtissues and spheroids, InSphero 3D InSight, MatTek HUREL micro livers, CN Bio PhysioMimix liver plates and others, with donor pooling, longevity in culture, published per-plate prices, production schedules and shipping arrangements.

Price analysis
Buying reconstructed human epidermis: models, validation, kit sizes and calendars

A buying guide for reconstructed human epidermis, which models hold OECD TG 439 and TG 431 validation, what a kit contains, verified shipping cadence and shelf life, QC-on-arrival procedure, and the one supplier that publishes a full price list.

Price analysis
Endothelial cells: the guarantee is written in the supplier medium, and it is not portable

A sourcing guide for human vascular endothelial cells, HUVEC and microvascular, covering published passage at ship, population doubling guarantees, the pre-screening premium, pooled versus single-donor lots, named pathogen panels and the SKU pair that shows what a cell price actually buys.

Price analysis
Engineered heart tissue: who sells the plate, who sells the tissue, who sells the data

A sourcing guide to engineered heart tissue, myriamed myrPlate and myrTissue-Cardio with published prices, Curi Bio Mantarray, Ncardia and DiNABIOS (formerly EHT Technologies), covering format, force readout, instrument lock-in, lead time and what each route actually commits you to.

Price analysis
Engineered skeletal muscle tissue: one supplier sells it, nobody specifies it

One supplier, myriamed, sells finished engineered skeletal muscle off a public storefront at EUR 1,400 per tissue. It publishes no force specification. This page names that option, the casting devices you can cast your own in, who will quote a custom programme, and the real published force numbers so you can judge a spec.

Price analysis
Fibroblasts and keratinocytes: age grade is a specification, and most purchase orders leave it blank

A sourcing guide for human dermal fibroblasts and keratinocytes, published prices from the one complete public price list in reconstructed tissue, why adult, neonatal and fetal grades are not interchangeable, matched-donor pairs for skin models, and the volume discount structure nobody uses.

Price analysis
Hepatocytes: the largest line item in a liver programme has no public price

A sourcing guide for human hepatocytes as cells rather than as a finished model, the three supply routes, the one published price, why a perfused liver plate consumes millions of unpriced primary cells, and the metabolic specifications to demand at release.

Price analysis
Human biospecimens: consent scope is the deliverable, and it is not on the invoice

A sourcing guide for consented human tissue, adipose, biofluids and disease-state specimens, banked inventory versus prospective collection, the regulatory posture a serious supplier holds, why almost nothing is publicly priced, and the consent question that decides whether your project is publishable or commercialisable.

Price analysis
Human iPSC-derived cortical neurons: what is actually available

An availability table for human iPSC-derived cortical neurons across named suppliers, subtype, published purity specification, markers, format, lead time, licence class and price band, each traced to the supplier source it came from.

Price analysis
Human skeletal myoblasts: who publishes what, and what they leave out

A supplier table for human skeletal myoblasts and muscle-derived cells covering donor disclosure, passage at ship, purity marker and threshold, whether fusion index is reported, price and lot variability, and what no supplier specifies.

Price analysis
iPSC-derived astrocytes, microglia and oligodendrocytes: what to buy and at what ratio

Prices and specifications for human iPSC-derived astrocytes, microglia, oligodendrocytes and OPCs across named suppliers, plus the neuron-to-astrocyte co-culture ratios and seeding densities used in published multielectrode array work, with citations.

Price analysis
iPSC-derived cardiomyocytes: what is actually available and what it costs

A sourcing table for human iPSC-derived cardiomyocytes across named suppliers, ventricular, atrial and nodal subtype availability, published purity specifications, beating and assay-ready timing, MEA and calcium-imaging validation, and list prices with the source and date for every figure.

Price analysis
iPSC-derived microglia: the medium is the specification

A sourcing guide for human iPSC-derived microglia across the suppliers that publish list prices, pack economics, the flat disease-line uplift, engineered backgrounds priced at wild type, and why the matched medium is a specification rather than an accessory.

Price analysis
iPSC-derived motor neurons: suppliers, purity and price per million

Published list prices for human iPSC-derived spinal motor neurons from iXCells, bit.bio, Axol and others, normalised per million cells, with the marker evidence each supplier publishes, the differentiation route where disclosed, and disease and isogenic line pricing.

Price analysis
Isogenic iPSC pairs: the distribution fee is published, the licence that decides commercialisation is not

A sourcing guide for matched mutant and corrected iPSC lines from the public banks, both published fee tiers at Coriell, RIKEN and EBiSC, the separately charged licence line item, what a two-tier price does and does not grant, and the specification checklist for an isogenic pair.

Price analysis
Leukopaks and apheresis products: nothing is publicly priced, and the recallable donor is the thing to ask for

A sourcing guide for PBMCs, leukopaks and isolated immune subsets from apheresis donors, the three supplier models and what actually separates them, recallable donor programmes for longitudinal design, why the pre-analytical window decides between inventory and prospective collection, and the specification checklist for a cohort quote.

Price analysis
MEA-ready neurons: what the phrase means and what to check instead

A compatibility matrix of iPSC neuron products against Axion Maestro, MaxWell MaxTwo and Multi Channel Systems MEA platforms, plate formats, electrode counts, seeding densities, days to bursting and co-culture requirements, and why "MEA-ready" carries no agreed definition.

Price analysis
Neural stem cells: you are buying expansion headroom, and one consent restriction can end a project

A sourcing guide for human iPSC-derived neural stem cells and neural progenitors, published prices across two suppliers, the disease-line premium, what expandability is actually worth against buying differentiated neurons, and the donor consent restriction that propagates silently to derived products.

Price analysis
Oligodendrocytes and OPCs: one supplier publishes a price, and that is the finding

A sourcing guide for human iPSC-derived oligodendrocyte-like cells and OPCs, the single published price in the category, the lineage premium against astrocytes and microglia, why maturation duration dominates the true cost, and what to ask when there is no second quote.

Price analysis
Rodent and immortalised lines: the cheapest vial should carry the rehearsal, not the experiment

A sourcing guide for rodent and immortalised cell lines used to qualify protocols before human material is committed, published prices against their human equivalents, where the substitution is legitimate, where published work says it is not, and why regional variants leave the catalogue entirely.

Price analysis

Comparisons 13

Entry Type
3D skeletal muscle models compared: device, cell source, force readout and cost per data point

A comparison matrix of 3D skeletal muscle models, Curi Bio Mantarray, eNUVIO OMEGA-MP, Duke myobundles, myriamed myrPlate and myrTissue-Skeletal, and CYTOO MyoScreen, on cell source, device, force readout, maturation time, throughput and cost per data point, with published force figures.

Comparison
3D tissue model suppliers compared: what ships, what is custom, and what it costs

A comparison of fourteen 3D tissue model suppliers, MatTek, EPISKIN, InSphero, MIMETAS, Emulate, CN Bio, TissUse, Altis, Visikol, Xellar, Phenion, J-TEC, myriamed and eNUVIO, on tissue types, format, whether they ship finished tissue or an empty device, custom capability and published price band.

Comparison
Cell banking providers compared: commercial, institutional and the quote-only wall

A head-to-head of cell banking providers, WiCell, Cook MyoSite, uBriGene, Curi Bio and named institutional cores, on published price, what is included in the release panel, grade, turnaround, deposit-for-distribution options and who owns the resulting bank.

Comparison
Contract differentiation providers compared: who will actually hand you the cells

A head-to-head of contract iPSC differentiation providers, Curi Bio, Ncardia, Axol, bit.bio, Cook MyoSite, eNUVIO and FUJIFILM CDI, on lineages, whose line they will work on, published acceptance criteria, timelines, engagement models and the question that decides the purchase: whether the deliverable is cells or a report.

Comparison
EpiDerm vs SkinEthic RHE vs EPiTRI: reconstructed human epidermis compared

A head-to-head of the validated reconstructed human epidermis models, barrier function and ET-50 acceptance ranges, protocol parameters, OECD TG 439 and TG 431 validation status, formats, lead time and what is actually published about price.

Comparison
iPSC astrocyte suppliers compared, head to head

An even-handed head-to-head of human iPSC-derived astrocyte suppliers, price per million, published functional evidence, co-culture protocol support, disease panels, isogenic partners and licence posture, with the co-culture ratio the literature actually used and a note on where primary astrocytes still win.

Comparison
iPSC neuron suppliers compared, head to head

A head-to-head of the main human iPSC-derived neuron suppliers, price per million, purity specification, subtype breadth, line provenance, published electrophysiology, licensing and minimum order, with a clear statement of where each one is strongest.

Comparison
Liver model suppliers compared: spheroids, perfused chips, hepatocytes and cell lines

A head-to-head of human liver model suppliers, InSphero 3D InSight, MatTek HUREL micro livers, CN Bio PhysioMimix perfused plates, HepaRG and bit.bio ioHepatocytes, on model architecture, donor pooling, longevity, format, published price and what each route actually costs per data point.

Comparison
MEA platforms compared: electrode counts, recording channels and per-well economics

A head-to-head of the five multielectrode array platform families, Axion Maestro, MaxWell MaxOne and MaxTwo, Multi Channel Systems, 3Brain CorePlate and Alpha MED MED64, on electrodes per well, simultaneous recording channels, plate reuse, published cell-product protocol support and the per-well economics no vendor will publish.

Comparison
Microfluidic fabricators compared: method, feature size, tolerance, MOQ and NRE

A head-to-head of named microfluidic fabricators, HiComp, Parallel Fluidics, eNUVIO, FlowJEM, Blue BioDevice, uFluidix, microfluidic ChipShop, Potomac Photonics, ALine and an academic cleanroom, on fabrication method, material, minimum feature size, published tolerances, minimum order quantity, non-recurring engineering cost and who keeps the tooling.

Comparison
Organ-on-chip platforms compared: Emulate, MIMETAS, CN Bio and six others

Eight organ-on-chip platforms against throughput, perfusion mechanism, membrane versus scaffold-free architecture, imaging compatibility, open versus closed consumables and published tissue models. No vendor publishes consumable pricing, that column is honestly empty.

Comparison
Organ-on-chip vs Transwell vs static culture: a decision matrix

Three culture architectures compared on physiological relevance, cost per data point, throughput and hands-on time, including an explicit account of when a Transwell insert is the right and cheaper answer, which is more often than the field admits.

Comparison
Skeletal myoblast sources compared: primary, iPSC-derived and immortalised

A head-to-head of the three routes to human myogenic progenitors, primary from Cook MyoSite, PromoCell and Lonza, iPSC-derived from iXCells, bit.bio and myriamed, and immortalised lines, on price per million, purity marker, passage window, donor authenticity, disease panels and what each route costs you scientifically.

Comparison

Services 14

Entry Type
Contract cell and tissue services: what to outsource and what it costs

A service taxonomy for cell and tissue work: what each service is priced on, how long it takes, and the specific conditions under which outsourcing beats doing it in-house. Includes the three cases where in-house is clearly correct.

Section index
Assay-ready plating: when paying someone else to plate your cells is rational

Who supplies cells already in the plate, in which formats, live or frozen, and how to work out whether the premium beats your own technician hours. An under-served niche with a genuinely narrow set of cases where it is the right purchase.

Price analysis
Buying cryogenic dry shipper hire: the rental is a month, the charging is a competence, and the logger is optional

For anything that must stay below minus 150 C, dry ice is not sufficient and a liquid nitrogen vapour shipper is required. Unlike most of cold chain, these are rented at published rates, and the published rates say three things buyers consistently get wrong.

Price analysis
Buying electrophysiology characterisation as a service: the option most often skipped

One institutional core publishes a full rate card for MEA recordings, imaging and project planning. Set that against a six-figure instrument, a five-figure service contract and a seven-week maturation, and below about one plate a month the arithmetic is not close.

Price analysis
Buying mycoplasma, sterility and endotoxin testing: two assays with the same name are not the same test

Published rates for contamination and compendial release testing, with the method stated for each, and the line item that produces a first invoice several times the budget: method validation, charged once per matrix and invisible on every per-sample price list.

Price analysis
Buying research cell banking and cryostorage: freezing vials is cheap, proving what is in them is not

Banking a line you already own is priced per vial at institutional cores and per programme at commercial providers, and the two are priced on different bases. This is the published arithmetic, the three bank types, and why karyotype is half the release panel.

Price analysis
Buying STR identity and karyotype authentication: why the same test costs $65 and $250

The same nominal STR assay ranges four-fold across published rate cards, and the cheap end is frequently a rate you cannot access. This is what separates the providers, loci count, database comparison, signed interpretation, and when karyotype stops being optional.

Price analysis
Contract cell culture services: providers, scope and how they charge

Who will culture, expand, differentiate, bank or plate cells for you, at what scale, under RUO or GMP, and on what price basis. Cook MyoSite runs a 3,470 sq ft ISO 7 / ISO 5 cleanroom for muscle cell manufacture; almost nobody publishes a rate.

Price analysis
Custom iPSC differentiation services: scope, timeline and what the price is actually based on

Seven providers of contract iPSC differentiation compared on lineages offered, whether they will work on your line or insist on theirs, QC deliverables, published timelines and price basis. Includes the only published phase durations in the category.

Price analysis
Custom microfluidic device fabrication: getting quotes you can actually compare

Which fabrication method suits your feature size, what each fabricator will and will not take on, and the twelve-item specification checklist that makes two microfluidic quotes comparable instead of merely different.

Price analysis
Custom organ-on-chip development: who builds what, and on whose platform

Ten organ-on-chip providers mapped against platform lock-in, tissue types supported, perfusion mechanism, imaging compatibility, whether they sell a product or a service, and the engagement model each will actually sign. Plus the scoping questions that decide the price.

Price analysis
Custom primary cell isolation: who will isolate what, from which tissue, under whose consent

Seven providers of contract primary cell isolation compared on tissue types, donor sourcing and consent posture, yield expectations and price basis. Includes what a defensible consent chain looks like and why nobody guarantees yield.

Price analysis
PDMS device fabrication: what a real quote includes

A PDMS device quote has six cost centres, master, casting, bonding, surface treatment, sterilisation and QC. Most first-round quotes price two of them. This page shows the full anatomy and a comparable quote structure you can send to any shop.

Price analysis
Tissue engineering CROs: directory and capability matrix

Fourteen organisations that will quote tissue engineering work, mapped against scaffold, bioprint, muscle, skin, vascular and organ-on-chip capability, regulatory scope, instrumentation and engagement size, including which parts of this market have closed down.

Directory

Devices 13

Entry Type
Custom culture devices, microfluidics and organ-chips

Three routes to a culture device: buy off the shelf, modify something that exists, or fabricate from scratch. This page sets out what each route costs, how long it takes, and the questions that decide which one you are actually on.

Section index
3D printing a culture device: what the resolution really is, and whether the resin kills your cells

Commercial resin printers resolve at 50 µm pixels, not at microfluidic scale, research printers reach 18 µm and below. This sets out the resolution ceiling, the resin cytotoxicity problem, the published biocompatibility data and when printing beats moulding.

Guide
Buying 3D-printed culture device prototyping: what printing is genuinely good at, and the two ways it fails

Printing a culture device is faster than moulding one and fails in two ways soft lithography does not: the resolution is worse than the pixel size implies, and the resin can be cytotoxic. This is how to scope, specify and accept a printed prototype without losing a batch of cells to it.

Price analysis
Buying MEA plates and electrode arrays: format, reuse and the cost you cannot see before you commit

Every multielectrode array vendor publishes a complete electrode specification and no price. This is the buying guide: what separates Axion, Multi Channel Systems, MaxWell, 3Brain and Alpha MED, the derived transaction prices we could evidence, and the commercial terms that decide the three-year bill.

Price analysis
Buying organ-on-chip plates and chip consumables: price per chip, chip material, and the ecosystem you cannot leave

AIM Biotech publishes a full price list; MIMETAS, Emulate and CN Bio publish none. This is the per-chip arithmetic across platforms, the derived procurement anchors with their caveats stated, and why chip material is a scoping decision rather than a detail.

Price analysis
Buying perfusion and flow control hardware: shear stress is a property of the channel, not the pump

A rocker and a pressure controller are not two price points for the same thing. This is the procurement guide to perfusion hardware, ibidi list prices verified 2026-09-01, the published shear coefficients that vary fifteen-fold across one product family, and the specification line that stops you reporting a shear stress your cells never saw.

Price analysis
Buying SU-8 masters and PDMS chip fabrication: the two numbers in every quote, and the contract term that doubles your second order

A handful of fabricators publish rate cards, which makes soft lithography one of the few custom processes you can cost before opening a sales conversation. This is that arithmetic, published NRE and per-part figures, the amortisation curve, and the single RFQ line most buyers omit.

Price analysis
Perfusion and flow control: rockers, pumps and pressure controllers, and what each one costs

A rocker costs nothing per channel and gives you bidirectional gravity flow. A pressure-driven pump costs five figures and gives you a defined shear stress. This sets out the four perfusion routes, their published shear stress relationships and the live-verified prices.

Comparison
SLAS plate format: the dimensions your custom device must hit, and what breaks when it misses

The ANSI/SLAS microplate standards give five numbers a custom culture device must respect to work with the imager, the liquid handler and the plate reader you already own. This is what each one is, where the tolerance sits, and which failures are recoverable.

Guide
Spheroid and organoid microwell plates: aggregates per well, and what each format costs

AggreWell, Sphericalplate 5D, Corning Elplasia, InSphero Akura and Gri3D produce between one and 12,000 spheroids per vessel. This compares published microwell counts, cell loading ranges and materials, with the live-verified list prices where they exist.

Comparison
Sterilising a custom culture device: five methods, and what each one does to your part

Autoclaving is free and deforms thermoplastics. Gamma is a service and changes polymer crosslinking. EO leaves residuals with published limits. This sets out the five sterilisation routes against material compatibility, surface treatment survival and what to write into a device specification.

Guide
Surface treatment for culture devices: plasma, coatings, and how long each one lasts

Plasma treatment turns PDMS hydrophilic and it starts reverting within minutes. This sets out the published contact-angle data, the storage protocols that extend the window, the ECM coating options, and what to write into a device specification so the surface arrives usable.

Guide
Transwell inserts and permeable supports: pore size, membrane material and the TEER number

Corning publishes growth areas, pore densities and membrane characteristics for every Transwell format. This is that data assembled, plus why a TEER value measured with chopstick electrodes is not comparable to one measured any other way.

Guide

Tissue 13

Entry Type
Engineered tissue: what you can actually buy

An availability map of engineered human tissue by type, which are shipped as off-the-shelf living products, which are custom programmes, and which exist only in academic laboratories, with the supplier count and the evidence behind each classification.

Section index
Alveolar lung tissue models: two routes, neither of them priced

The alveolus splits into a finished static insert tissue and a perfused chip you seed yourself. Neither route publishes a price. This page sets out what each one actually delivers, the two-week stability statement that ends most repeat-dose studies, and the only instrument figures that exist, which are derived from federal awards and are upper bounds.

Price analysis
Blood-brain barrier models: one route publishes every number, the other publishes none

The self-assembly BBB route is priced end to end on a public storefront, down to the supplement and the per-chip cost. The prepared perfused route removes the seeding skill requirement entirely and publishes no price at all. This page sets out both, checks the bundle arithmetic, and names the field that should decide between them.

Price analysis
Buying airway and respiratory tissue: nose, bronchus, bronchiole and alveolus

A sourcing guide to off-the-shelf human airway tissue, MatTek EpiAirway, EpiNasal and EpiAlveolar, Epithelix MucilAir, SmallAir and AlveolAir, with verified TEER release criteria, culture longevity, donor disease panels, anatomical region mapping and the post-shipment QC problem nobody mentions.

Price analysis
Buying corneal and ocular tissue: four validated models and what separates them

A sourcing guide to reconstructed human cornea-like epithelium, EpiOcular, SkinEthic HCE, LabCyte CORNEA-MODEL24 and MCTT HCE, with the OECD TG 492 prediction model cut-offs, published QC batch release ranges, exposure protocols and what the guideline says these models cannot do.

Price analysis
Buying intestinal tissue models: planar epithelium, crypts, organoids and perfused tubules

A sourcing guide to human intestinal tissue models, Altis RepliGut Planar and Crypt, MatTek EpiIntestinal, MIMETAS OrganoReady Colon and CN Bio gut plates, covering regional identity, the planar-versus-organoid geometry decision, published Caco-2 comparisons, time to a working barrier and what to specify in a quote.

Price analysis
Buying oral, gingival and mucosal tissue: the epithelia outside the guidelines

A sourcing guide to human mucosal tissue models, MatTek EpiOral, EpiGingival and EpiVaginal, EPISKIN SkinEthic HGE, HO2E, HBE and HVE, covering non-keratinised versus keratinised mucosa, why most of this category sits outside OECD validation, and what to specify when there is no acceptance criterion to point at.

Price analysis
Cardiac microtissues: the plate costs $59.75, the finished tissue has no price at all

Scaffold-free cardiac microtissues answer beat rate, calcium handling and viability questions and cannot answer absolute force questions. This page sets out the geometry decision that must be made before any money moves, the publicly priced self-forming route, and why no supplier surveyed publishes a price for a finished cardiac microtissue.

Price analysis
Kidney proximal tubule models: you can buy every part except the tubule

Human renal proximal tubular epithelial cells carry live list prices at two suppliers and perfused culture plates carry live list prices at a third. No supplier surveyed sells a released, barrier-verified proximal tubule model against a TEER or transporter acceptance criterion. This page prices the parts and states plainly what the assembly costs you in risk.

Price analysis
Organoids versus engineered tissue: a geometry decision, not a quality ranking

The practical difference between self-organising organoids and engineered tissue constructs, apical access, assay compatibility, batch variability, Matrigel dependence and the oxygen diffusion limit, and how the choice determines which suppliers and which assays are available to you.

Guide
Production calendars and shelf life: the constraint that decides your start date

Living tissue is manufactured to a calendar, not held in inventory. The published shipping cadences, order-by dates, shelf lives and post-shipment QC windows from MatTek, Epithelix and InSphero, and how to plan a study around a supply that does not exist until it is made.

Guide
Tumour spheroids: every input is public-priced and the finished plate is not sold

Cancer cell lines at $577.00, spheroid microplates at $59.75, ECM-patterned chips at $7.60 per experiment, and no supplier selling a released plate of size-specified, viability-verified spheroids. This page prices the self-assembly route and explains why microwell diameter is the decision that determines whether your model works at all.

Price analysis
Vascularised thick tissue: why you cannot buy it, and what you can buy instead

Engineered tissue stops at roughly 100–200 µm without a blood supply. What that physical limit means commercially, what vascular models actually ship today, what the bioprinting literature has demonstrated, and how to specify a thick-tissue project honestly.

Guide

Biohybrid robotics 10

Entry Type
Biohybrid robotics: sourcing living actuators

A landscape map of biohybrid actuator work, which groups build what, from which cell source, with what published force, and the honest supply-side answer: finished contractile tissue is purchasable from one supplier at EUR 1,400, but nobody sells it against a force specification, so every project is still an integration job.

Section index
Biohybrid actuator bill of materials: every line item, priced where a price exists

A complete parts list for one engineered muscle actuator, from cells to force readout, with a published price where one exists and an explicit "quote only" where it does not. Verified prices: eNUVIO $440, ATCC $577, myriamed EUR 1,400.

Guide
Biological computing hardware: what you can actually buy, rent or collaborate on

The commercial and academic landscape for neurons-as-compute: Cortical Labs CL1 and Cortical Cloud, FinalSpark Neuroplatform, and the general-purpose HD-MEA route. Substrate, electrode counts, access model and published prices, with sources and dates.

Guide
Cardiac or skeletal muscle: choosing an actuator substrate

Cardiac muscle contracts by itself and never stops. Skeletal muscle does nothing until you tell it to, then does exactly that. Published forces, control models, lifetimes and commercial supply for both, with a citation on every claim.

Comparison
Cell culture for a robotics lab: what you actually have to build

What an engineering group must acquire, learn and staff before it can make a living actuator, and the one verified price that finally makes the make-versus-buy comparison answerable: myriamed lists a finished skeletal muscle tissue at EUR 1,400.

Guide
Engineered muscle force: a normalised reference table

Published twitch and tetanic forces for engineered skeletal muscle, normalised to specific force in mN/mm² alongside cross-sectional area and stimulation protocol, with a citation on every row. The reference table for anyone writing a force specification.

Guide
Muscle actuator sourcing: C2C12, primary human, iPSC or insect

Four cell sourcing routes for a biohybrid muscle actuator compared on cost, maturation time, published force, culture burden, approval burden and who will actually supply them. C2C12 is the default and it is a mouse cell line.

Guide
Neuron-driven actuators: sourcing a working neuromuscular junction

Putting motor neurons in command of engineered muscle adds a biological control layer to a biohybrid device. What the published work achieved, how the curare test proves a junction is real, and what you have to buy to attempt it.

Guide
Optogenetic muscle control: what you have to source to drive tissue with light

Light-driven muscle actuation buys spatial addressing that electrodes cannot give, at the cost of a genetic modification step. Published forces, the 84 percent figure against electrical stimulation, and the four things you must actually acquire.

Guide
The operating envelope: what a living actuator needs to keep working

Living actuators run at 37 °C in buffered media inside a sterile incubator, and published untethered lifetimes are measured in days. The environmental constraints, the one documented ambient exception, and what that means for device design.

Guide

Buying guides 18

Entry Type
How to buy wetware

An end-to-end procurement flow for engineered living components, from specification through supplier selection, licensing, QC, shipping and acceptance, with a checklist for each of the eight stages.

Section index
Building a blood-brain barrier model

A problem-first route to a working BBB model: the four buildable routes and what each measures, honest TEER targets and why the literature spans four orders of magnitude, the cell identity controversy you must know before choosing a protocol, published prices where they exist, a MODELLED insert-based budget, and a specification checklist.

Guide
Building an MEA-based neurotoxicity assay

A problem-first route to a working microelectrode array neurotoxicity assay: what the published EPA screening campaigns actually measured, the cells and plates you need with real prices, the buy-versus-outsource instrument decision, a MODELLED bill of materials for 24- and 48-well pilots, and a specification checklist.

Guide
Cell line licensing for commercial use

What research-use cell line terms actually permit, quoted from published ATCC, EBiSC, Coriell and bit.bio agreements. The right to sell a differentiated derivative is almost never included in the purchase price.

Guide
Cell supplier QC checklist: 15 items

A 15-item quality control checklist for buying cells: what each item is, why it matters, what an acceptable specification looks like, the red flag to watch for, and whether suppliers provide it as standard.

Guide
Choosing a microfluidic material: PDMS, COP, COC, PMMA, PS and glass

PDMS absorbs hydrophobic small molecules badly enough to invalidate pharmacology. This is the material matrix, absorption, optical clarity, gas permeability, autofluorescence, bondability, scalability and cost per part, with the published absorption data laid out properly.

Guide
How to compare two custom biology quotes

A normalisation worksheet for custom biology quotes: the twelve line items that must be present, the terms that decide who pays for a failed batch, and two worked examples, quotes that look different and are identical, and quotes that look identical and are not.

Guide
MEA platform compatibility matrix: plate formats, electrode counts and what fits what

Published plate formats and electrode counts for Axion Maestro, MaxWell MaxOne and MaxTwo, Multi Channel Systems, 3Brain CorePlate and Alpha MED Scientific MED64, with coating requirements and which cell products have published protocols on each.

Guide
OECD TG 439: what a compliant RhE model must demonstrate

The requirements a reconstructed human epidermis model must meet under OECD Test Guideline 439, tissue construction, barrier function expressed as ET-50 or IC50, the MTT viability assay, controls, run acceptance criteria and the prediction model, plus which commercial models hold validation and how TG 431 relates.

Guide
Realistic lead times for cells, tissue and custom devices

Observed lead times across 26 offerings, catalogue cells, living tissue models, engineered tissue, custom microfabrication, contract culture and QC, with what actually drives the variance and why a six-week quote becomes eleven weeks.

Guide
Replacing animal skin testing: the OECD TG 439 and TG 431 route

A problem-first sourcing route out of the rabbit skin test: which guideline answers which question, how many tissues a run actually consumes, what is purchasable and at what published price, the weekly production cadence that sets your schedule, and a specification checklist for an RhE quote.

Guide
Running a cardiotoxicity screen in six weeks

A problem-first sourcing route for a cardiac safety screen: which readout answers your question, which cardiomyocyte SKUs have published prices, a modelled bill of materials for a 48-well MEA pilot and a 96-well plate, a week-by-week timeline, and a specification you can send to suppliers.

Guide
Scaling from pilot to screening

What actually breaks when a working 6-well experiment becomes a 384-well screen: the growth-area disagreement that changes your cell order by 50 percent, the volume tiers that decide the budget, edge effects, lot boundaries, plate lead times, a MODELLED cost comparison across formats, and a re-quote checklist.

Guide
Setting up a liver model programme

A problem-first route to a working hepatic toxicity capability: which of the four liver model routes answers your question, the only published per-microtissue price in the category, a staged budget that defers the expensive decision, realistic timelines, and a specification checklist.

Guide
Shipping live cells and tissue

The four shipment formats for living material compared on viability risk, cost, customs and IATA treatment, and what to test on arrival. Includes the verified MatTek cold-chain model: 4°C on agarose gels, fixed weekly cadence, four-day shelf life including transit.

Guide
Sourcing under a grant deadline

A triage method for buying living material against a fixed date: the four hard constraints no budget can shorten, the six soft ones you can attack, what is achievable at four, eight, twelve and twenty-six weeks, decision tables by material class, and the escalation language that actually works.

Guide
Vials to wells: how many cells your experiment actually needs

Reference tables of published growth areas per well for 6 to 384-well plates and MEA formats, sourced seeding densities for neurons and cardiomyocytes, cells per well, wells per one-million-cell vial, and a worked 48-well MEA calculation with honest correction factors.

Guide
Your first iPSC experiment, from line choice to first result

A problem-first route for a laboratory with no iPSC experience: the buy-differentiated-versus-differentiate-yourself decision, line and repository choice with published fees, the QC panel and what it costs, a MODELLED first-experiment budget, a realistic timeline, and the specification to send.

Guide

Supplier directories 8

Entry Type
The master supplier directory

Every organisation we hold evidence for across cells, tissue models, contractile tissue, culture devices, native tissue, contract manufacturing, QC and cold chain, with what each actually supplies, its region, whether it publishes a catalogue price, its RUO or GMP posture, and how strong our evidence is. Including the ones that have exited.

Section index
Bioprinting suppliers: who is still selling, what it costs, and who has already left

A directory of 3D bioprinter and bioink suppliers covering extrusion, light-based and volumetric platforms, with published consumable prices, which vendors gate instrument pricing behind a quote, and a dated record of the exits, including the Allevi end-of-service-life date that has already passed.

Directory
Biospecimen suppliers: the directory, and the consent question nobody puts on the invoice

A directory of human and animal biospecimen suppliers, marketplaces, biorepositories, direct-to-patient collectors and animal tissue catalogues, covering prospective versus inventory collection, contracting structure, specimen classes, published prices and which vendors block verification.

Directory
Hydrogel and ECM suppliers: the directory, and the case against the default

A directory of extracellular matrix and hydrogel suppliers for 3D culture, basement membrane extracts, animal and human collagens, GelMA and photo-crosslinkable inks, and fully defined synthetic systems, with species of origin, whether stiffness is a specified parameter, and published prices.

Directory
iPSC line suppliers and banks: a directory organised around the licence, not the price

A directory of human iPSC line sources, WiCell, Coriell, RIKEN BRC, EBiSC, ATCC and the commercial banks, with distribution fees at both academic and commercial tiers, the agreement each requires, who owns the underlying reprogramming patents, and what each will not let you do with a derivative.

Directory
iPSC neuron suppliers: a directory with the specifications attached

A directory of named human iPSC-derived neuron suppliers with the columns that actually matter, subtypes offered, published purity, whether MEA data is published, line provenance, licensing posture, minimum order, lead time, region, RUO/GMP status and price band.

Directory
Organoid suppliers: a directory, and the licence sitting under most of the market

A directory of organoid model suppliers, biobanks and expansion services, adult stem cell versus iPSC-derived routes, tissue coverage, whether models are sold or only screened against, and the HUB technology licence that separates academic purchase from commercial use.

Directory
Primary human cell suppliers: the directory, and the three numbers that decide a lot

A directory of named primary human cell suppliers with the columns that decide whether a lot is usable, passage at ship, guaranteed population doublings, the pathogen panel, donor disclosure, delivery format and published price, with the source and date for every figure.

Directory

Glossary 15

Entry Type
Wetware glossary

An A–Z reference of terms used in buying and specifying engineered living components: cells, engineered tissue, culture devices and the QC, licensing and logistics vocabulary around them. Over 60 terms, each with a one-line definition.

Section index
Certificate of analysis: how to read one, and what it does not cover

A CoA is a lot-specific record of tests actually performed on the material you are receiving. It is not a datasheet, not a specification, and not a warranty of function. What each line means, the four questions that expose a weak CoA, and what to demand before you order.

Definition
Cryopreservation and thaw: what the parameters mean and which ones matter

DMSO concentration, controlled-rate versus passive freezing, vapour-phase versus liquid-phase nitrogen storage, and thaw technique. What each parameter does mechanistically, what the evidence supports, and what to specify when buying cryopreserved cells.

Definition
Differentiation protocol routes: NGN2, dual-SMAD and direct conversion

The three main routes to human neurons in vitro compared on time to maturity, purity, subtype fidelity, cost, network activity and when each is appropriate. NGN2 induction is fast and homogeneous; developmental cortical protocols run around 80 days.

Definition
Electrophysiology readouts compared: what each measures and what it costs in effort

Multielectrode array, manual and automated patch clamp, calcium imaging and voltage indicators measure different physical quantities at different resolutions. What each actually records, throughput and invasiveness, what each cannot see, and how to choose for a specific question.

Definition
Engineered living component (ELC): definition and scope

An engineered living component is a living biological construct produced to a written specification, intended to function as a part within a larger system. Definition, taxonomy, boundary cases, and relation to tissue engineering, biofabrication and synthetic biology.

Definition
Isogenic controls: definition, how they are made, and what to check

An isogenic control is a cell line genetically identical to its comparator except at the edited locus. Why unmatched controls make disease-modelling data uninterpretable, how isogenic pairs are generated, and the six things to verify before buying one.

Definition
Matrigel and extracellular matrix substrates: what each is and where lot variability bites

Matrigel is an undefined tumour-derived basement membrane extract; laminin, vitronectin and fibronectin are defined single-protein or recombinant substrates. What each provides, which integrins they engage, where lot-to-lot variability comes from, and how to plan a substrate switch.

Definition
MEA-ready: definition, and the seven things to verify

MEA-ready is an undefined marketing term for neuron products sold for multielectrode array use. Here is the checklist of seven attributes that actually determine whether a product will produce network activity on an MEA.

Definition
Passage number vs population doublings: what a P-number actually tells you

Passage number counts subculture events, not cell divisions, and is not comparable between suppliers because split ratios differ. Population doubling level is the transferable unit. How to convert, what senescence thresholds mean, and what to demand on a datasheet.

Definition
Post-thaw viability: what the number means

Post-thaw viability is the percentage of cells in a thawed cryopreserved vial judged alive by a stated assay at a stated time. Method comparison across trypan blue, AO/PI and plating efficiency, and why vendor numbers are not comparable.

Definition
RUO vs GMP cells: what actually differs

RUO cells are supplied for research use only with no regulatory manufacturing standard behind them; GMP cells are manufactured under a quality system for clinical use. Comparison of documentation, testing, price, permitted use, and when RUO is sufficient.

Definition
Seed train, master and working cell banks: the terms and what they cost you

A seed train is the staged expansion from a thawed vial to production scale. What master and working cell banks are under ICH Q5D, why the two-tier structure exists, what expansion capacity actually limits, and what to ask when a supplier quotes a batch.

Definition
Sterility and mycoplasma testing: the methods and what a negative result establishes

Sterility testing and mycoplasma testing are separate tests covering different organisms; neither substitutes for the other. The compendial methods, PCR versus culture detection limits, why a negative result is not the same as absence, and what to demand on a CoA.

Definition
What belongs in a wetware RFQ

A complete field checklist for requesting quotes on cells, engineered tissue and custom culture devices, plus a fully worked example RFQ. Written so two suppliers quoting the same document produce comparable numbers.

Definition

Site 14

Entry Type
Capabilities

Nine sourcing categories, with lead time, delivery format, QC scope and quote type for each.

Page
Catalogue index

Sourceable entries, with the manufacturer stated on every entry.

Page
How it works

Roles, ordering sequence, fee structures and limits.

Page
Request a quote

Submit one specification and receive comparable quotes.

Page
Sourcing methodology

How suppliers are researched, and what each verification label means.

Page
The WWD standard

An open file format for describing a living component.

Page
Why a file format

A machine-checkable package compared with a specification PDF.

Page
Validate a package

Check a WWD package against the schema in your browser. Nothing is uploaded.

Page
Examples and schemas

Reference packages and JSON schemas.

Page
Participate

How to comment on the standard and propose changes.

Page
About

Scope, completed work, operating rules and buyer types.

Page
Contact

Where to send a specification, and where to send everything else.

Page
For suppliers

What suppliers are sent, what is expected back, and how to get onto the sourcing list.

Page
Legal and policies

Terms, privacy, research-use restriction, export and biosecurity, shipping, confidentiality.

Page