Partner manufactured Verified against a primary source

High-Density MEA-Plated Culture (Thousands of Electrodes per Well)

Name: High-Density MEA-Plated Culture (Thousands of Electrodes per Well)
SKU: WW-NI-39204

Neuronal or cardiac cultures plated onto CMOS high-density arrays giving thousands of bidirectional electrodes per well, for single-cell-resolution network structure rather than well-average activity.

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Category	Neural Cultures & Electrode Interfaces
Unit	One CorePlate at the specified well format, plated with the specified culture, or one plated well
Lead time	quote-dependent for hardware and plates; add the full neuronal maturation period, typically 4-8 weeks after plating, before the culture is recordable
Pricing	Indicative range held
Provenance	Partner manufactured
Data current	2026-09-03

Description

Electrode count per well is the specification that decides what question an array can answer, and the spread across the market is not incremental. A conventional multiwell plate gives 8 to 64 electrodes per well and reports a well-average firing rate. A CMOS high-density array gives thousands per well and reports network structure, connectivity and single-cell resolution. 3Brain is the vendor that makes this concrete and, despite being cited across our MEA and biological computing coverage, has had no catalogue entry until now. Its CorePlate range spans four formats with published specifications: CorePlate 6W 38/60 integrates 4,096 bidirectional electrodes per well over a maximum seeding area of approximately 40 square millimetres at 30 by 30 micrometre electrodes on a 60 micrometre pitch, with up to 2,304 electrodes recordable at 10 kilohertz or 1,024 at 20 kilohertz per well by selecting a subset, and different subsets available to maximise either recorded area or spatial resolution; CorePlate 24W 16/50 gives 1,024 electrodes per well over approximately 10 square millimetres at 35 by 35 micrometres on a 50 micrometre pitch, with all wells and all electrodes recording simultaneously for 24,576 total and a well volume of approximately 1.8 millilitres; CorePlate 96W 16/50 gives 256 per well with the same 24,576 simultaneous total and is stated to be the first 96-well HD-MEA capable of truly simultaneous recording from every well and every electrode; CorePlate 1W 38/60 gives 4,096 electrodes in a 64 by 64 grid over 3.80 by 3.80 millimetres at 21 by 21 micrometre platinum-coated electrodes on a 60 micrometre pitch. Every electrode in the range is bidirectional and usable for stimulation. The 6W pairs with HyperCAM Alpha and the 24W and 96W with HyperCAM Delta. The two numbers that matter commercially are the total and the simultaneous total, and they are not the same number: on the 6W you select a subset, so 4,096 electrodes per well does not mean 4,096 channels at once. Read the sampling-rate line before budgeting.

Why this is hard to buy today

The headline electrode count and the number of electrodes you can actually record at once are different figures on the same product, and only the headline appears in comparison material. On the 6-well format the array carries 4,096 electrodes per well but records at most 2,304 of them at 10 kilohertz or 1,024 at 20 kilohertz, so raising the sampling rate to resolve spike waveforms more than halves the channels available. With no published price for any plate or instrument in the high-density category, a buyer cannot even work out what the electrodes they lose to that trade-off were costing them.

Price evidence

3Brain publishes complete technical specifications for every CorePlate format and no price for any of them, and publishes no price for the BioCAM or HyperCAM instruments. The figures below are DERIVED from named US federal contract awards published on USAspending.gov. Each is a real transaction price for that buyer on that date and an UPPER BOUND rather than a list price, because the obligated amount may include shipping, installation, warranty or unstated line items, and federal buyers may hold negotiated schedule pricing unavailable to other customers. (1) BioCAM DupleX platform: $162,468.70 as a single obligation, DERIVED from award PIID 75N95023P00787, US Department of Health and Human Services to 3BRAIN AG, action date 2023-09-19. (2) A CMOS array system with 4,096 channels, described in the award as commercial product name BioCAM, manufacturer 3Brain, with US distribution done exclusively through ALA Scientific: $92,885.47, DERIVED from award PIID 75N98018P00521, HHS to ALA Scientific Instruments Inc, 2018-07-30, note this is a distributor transaction and predates the DupleX generation. Neither award description states a plate or consumable quantity, so NO per-plate figure for any CorePlate format is derivable from either record and none is offered. For cross-vendor scale on the same derived basis: MaxWell MaxTwo multi-well HD-MEA platform $219,450.00 under PIID 68HE0B23P0114, EPA, 2022-12-12; Axion Maestro Pro 768-channel MEA system $184,050.00 under PIID 36C24121P0737, 2021-07-12. The only STATED unit prices in the MEA consumable category are for conventional planar arrays from a different vendor, published in the Czech public contracts register: Multi Channel Systems 60MEA200/30iR-Ti-gr at EUR 328.00 each for 25 units and 60-6wellMEA200/30iR-Ti-tcr at EUR 399.00 each for 2 units, order confirmation 800-021322-1, 2024-10-14. Those are not high-density arrays and must not be read as a CorePlate price.

These are supplier list prices we located and recorded, not a quotation from Wetware World. Your price depends on quantity, specification and freight, and is only binding once issued in writing.

What you must specify

A quote cannot be produced without these. Anything you leave open, a supplier will assume, usually expensively.

#	Parameter
01	Electrodes per well required, and separately the number recordable SIMULTANEOUSLY, which is a different and smaller number on some formats
02	Sampling rate required, since the simultaneous channel count falls as sampling rate rises
03	Well format and throughput needed: 1, 6, 24 or 96 wells
04	Seeding area available per well and the plating density that follows from it
05	Whether stimulation is required, and whether every electrode must be bidirectional
06	2D culture, 3D culture, organoid, spheroid, brain slice, explanted retina or cardiac model
07	Cell source, subtype and genotype
08	Instrument compatibility, including which HyperCAM generation the plate must pair with
09	Coating protocol and the coating volume implied by the well volume
10	Network activity acceptance criterion at delivery

Quality documentation

Typically available with this item. What actually ships is confirmed on the quotation, per supplier.

Manufacturer plate specification including electrode count, pitch and seeding area
Certificates of analysis for all cell inputs
Pre-delivery activity record where a plated culture is contracted rather than an empty plate
Plating density and coverage confirmation
Viability, sterility and mycoplasma

Candidate suppliers

Organisations we have identified as capable. Listing does not imply a partnership, an endorsement, or that they have agreed to quote.

Organisation	Basis for inclusion
3Brain	Fetched live 2026-09-01. CorePlate 6W 38/60 confirmed at 4,096 bidirectional electrodes per well over approximately 40 square millimetres of maximum seeding area, 30 by 30 micrometre electrodes on a 60 micrometre pitch, up to 2,304 electrodes recordable at 10 kilohertz or 1,024 at 20 kilohertz per well by subset selection, with different subsets available to maximise recorded area or spatial resolution, and compatibility with HyperCAM Alpha. Marketed for brain slices, neuronal tissue, human iPSC-derived neuronal networks, brain organoids, spheroids and cardiac cultures. No price.
3Brain (CorePlate 24W and 96W)	Fetched live 2026-09-01. CorePlate 24W 16/50: 1,024 electrodes per well centred on approximately 10 square millimetres, 35 by 35 micrometre electrodes at 50 micrometre pitch, all electrodes across all wells recording simultaneously for 24,576 total, well volume approximately 1.8 millilitres, HyperCAM Delta compatible. CorePlate 96W 16/50: 256 electrodes per well, 24,576 simultaneous across the plate, stated as the first 96-well HD-MEA of its kind with truly simultaneous recording from all wells and every electrode, HyperCAM Delta compatible. No price on either page.
ALA Scientific Instruments	Named in US federal award PIID 75N98018P00521 (2018-07-30) as the exclusive US distributor for the 3Brain BioCAM CMOS array system. Relevant as the likely US purchasing route, and as a reminder to check distributor uplift against direct pricing. No published price for the 3Brain range.
MaxWell Biosystems	The competing high-density CMOS platform, MaxOne single-well and MaxTwo multiwell, with the highest published electrode count per well in the category. No list pricing published; held figures are derived from named federal awards and are upper bounds.
iXCells Biotechnologies	Public WooCommerce Store API returns live USD list prices per SKU, queried 2026-09-01. Supplies the neuronal and astrocyte inputs at published per-vial prices.

Sources

doc WW-NI-39204 · rev 2026-09-03 · research use only · prices indicative and not binding until quoted in writing