Brain Organoid on a Multielectrode Array
A 3D neural organoid coupled to an electrode array so that network activity inside the tissue, not just at its base, becomes recordable.
| Category | Neural Cultures & Electrode Interfaces |
|---|---|
| Unit | One organoid coupled to one array or well, delivered with a recorded activity baseline |
| Lead time | quote-dependent; the myriamed tissue alone is stated at 7-11 weeks order-related manufacturing, and network maturation continues for months after that |
| Pricing | Indicative range held |
| Provenance | Partner manufactured |
| Data current | 2026-09-03 |
Description
Putting an organoid on a flat electrode array creates a specific and under-acknowledged measurement problem: a planar array only senses the cells touching it, so a spherical tissue reports from its base while the interior remains dark. Every vendor approach in this category is an answer to that problem and they differ fundamentally. Multi Channel Systems offers perforated and three-dimensional arrays built specifically for slices and organoids and has the widest array range for the purpose. MaxWell sells an organoid holder and perfusion accessories that mechanically stabilise the tissue on a high-density array. 3Brain takes the most direct route with CorePlate 3D, a first-in-class CMOS chip design mounting 4,096 gold-coated sensory electrodes on coated pillars with integrated microfluidic channels and biocompatible polymer isolation, marketed on non-destructive anchoring, multiple uses and quick turnover, and on reproducible probing of cytoarchitecture with label-free deep access to biologically relevant neurons. The single-well CorePlate 1W-3D 38/60/90 is the format built for in vitro organoids and ex vivo brain slices. On the tissue side, one finished 3D neural tissue is purchasable at a published price and is worth knowing about even though it is not sold coupled to an array: myriamed's myrTissue-Brain WT is a bioengineered neuronal organoid of interconnected excitatory and inhibitory neurons with supportive astrocytes and oligodendrocytes, and the supplier describes a documented maturation trajectory rather than a static product, giant depolarising potential-like events in early culture mimicking early fetal network activity, a GABA polarity switch with reduced GDPs beyond 40 days indicating progressive maturation, complex network burst development after two months, and evidence for long-term potentiation. That maturation timeline is the real specification, and it is why organoid-on-MEA work is measured in months rather than weeks.
Why this is hard to buy today
A planar electrode array records only the cells physically touching it, so a spherical organoid reports from its contact face while the interior stays silent, and the vendor specification sheets quote electrode counts and pitches without ever stating what fraction of a 3D tissue those electrodes can actually see. The three vendors solving this solve it in incompatible ways, perforated arrays, a mechanical organoid holder, and electrodes mounted on pillars, and none of the three publishes a price for the solution, so a buyer cannot compare the approaches on cost or commit to one without a sales conversation per vendor.
Price evidence
No vendor sells an organoid pre-coupled to an electrode array, and no MEA vendor publishes plate or instrument list pricing at all. Two evidence classes are kept separate below. PUBLISHED LIST PRICE, for the tissue only and NOT coupled to any array: myriamed myrTissue-Brain WT, a bioengineered neuronal organoid from the W001 wild-type line, EUR 1,400.00 for 1 tissue (catalogue 24-1001-5001), EUR 5,400.00 for 5 (24-1001-5005) and EUR 8,000.00 for 12 (24-1001-5012), shipped at room temperature for use after 24 hours of recovery at 37 degrees Celsius, certificate of analysis per released batch, order-related manufacturing lead time 7-11 weeks. Captured from the public Shopify products endpoint live 2026-09-01, currency confirmed as EUR via the storefront cart endpoint on the same date. DERIVED FIGURES for the array side, these come from named US federal contract awards on USAspending.gov, are UPPER BOUNDS rather than list prices because the obligation may include shipping, installation, warranty or unstated line items, and federal buyers may hold negotiated schedule pricing unavailable to other customers: MaxWell MaxTwo multi-well HD-MEA platform, $219,450.00 under award PIID 68HE0B23P0114, US Environmental Protection Agency, 2022-12-12, with a second MaxTwo platform obligation of $215,100.00 under PIID 75N95020P00591, 2020-09-09 and a third of $176,600.00 under PIID 75N95020P00318, 2020-07-14; MaxWell MaxTwo plate consumables SUBSCRIPTION, $19,600.00 under PIID 68HE0B25P0211, EPA, 2025-01-28, which is an annual subscription commitment and NOT a per-plate price; MaxLab Live stimulation assay software obligated separately at $12,450.00 under PIID 68HERD25P0006, 2024-10-17. None of those award descriptions states a plate quantity, so no per-plate figure is derivable from any of them and none is offered. The only STATED unit prices anywhere in the MEA consumable category come from a supplier order confirmation published in the Czech public contracts register, and they are for planar single-well and 6-well arrays rather than 3D organoid arrays: Multi Channel Systems 60MEA200/30iR-Ti-gr at EUR 328.00 each for 25 units and 60-6wellMEA200/30iR-Ti-tcr at EUR 399.00 each for 2 units, order confirmation 800-021322-1 to Masaryk University Faculty of Medicine, 2024-10-14, with a stated minimum order value of EUR 500.00 net and an additional EUR 25.00 charge below it.
These are supplier list prices we located and recorded, not a quotation from Wetware World. Your price depends on quantity, specification and freight, and is only binding once issued in writing.
What you must specify
A quote cannot be produced without these. Anything you leave open, a supplier will assume, usually expensively.
| # | Parameter |
|---|---|
| 01 | Electrode geometry: planar array sensing only the contact face, perforated or 3D pillar array sensing into the tissue |
| 02 | Organoid diameter and age, and the array seeding area it must sit within |
| 03 | Anchoring method, and whether it must be non-destructive and reversible |
| 04 | Whether integrated microfluidic perfusion is required to keep the organoid core viable |
| 05 | Network activity acceptance criterion and the maturation age at which it is assessed |
| 06 | Whether the maturation milestones matter to the study, such as the GABA polarity switch or complex burst onset |
| 07 | Number of organoids and wells, and the replicate structure |
| 08 | Whether the buyer already owns an instrument the plate must match |
| 09 | Stimulation requirement, and whether every electrode must be bidirectional |
Quality documentation
Typically available with this item. What actually ships is confirmed on the quotation, per supplier.
- Certificate of analysis per released batch for the tissue
- Pre-delivery activity record where a coupled culture is contracted, which must be specified explicitly
- Organoid diameter and morphology record
- Viability at release
- Sterility
Candidate suppliers
Organisations we have identified as capable. Listing does not imply a partnership, an endorsement, or that they have agreed to quote.
| Organisation | Basis for inclusion |
|---|---|
| 3Brain | Fetched live 2026-09-01. CorePlate 3D described as a first-in-class 3D CMOS chip with 4,096 gold-coated sensory electrodes mounted on coated pillars, biocompatible polymer isolation, integrated microfluidic channels and a bidirectional cell-electronic interface with on-chip signal processing. Claims are reproducible probing of cytoarchitecture with label-free deep access, increased cell viability and compound delivery via the microfluidics, and non-destructive anchoring allowing multiple uses. CorePlate 1W-3D 38/60/90 is the single-well format for in vitro organoids and ex vivo brain slices. No price published anywhere on the site. |
| myriamed | Public Shopify products endpoint queried live 2026-09-01 returning variant SKUs and EUR prices for myrTissue-Brain WT; currency confirmed via the storefront cart endpoint the same date. Product body confirms interconnected excitatory and inhibitory neurons with supportive astrocytes and oligodendrocytes, GDP-like events in early culture, GABA polarity switch and reduced GDPs beyond 40 days, complex network burst development after two months, evidence for long-term potentiation, ambient shipping with 24-hour recovery and a 7-11 week lead time. Cites Zafeiriou et al. Nature Communications 11:3791 (2020). Sold as tissue only, not coupled to any array. |
| MaxWell Biosystems | MaxOne single-well and MaxTwo multiwell high-density arrays with an organoid holder and perfusion accessories. No instrument, plate or accessory list price is published; the figures held for this vendor are derived from named federal awards and are upper bounds. |
| Multi Channel Systems MCS GmbH | Widest array range in the category including 3D and perforated arrays built specifically for slices and organoids. Operates a public online shop restricted to its direct sales territory of Europe, Australia and New Zealand and requiring an account, so prices are not openly published; the stated unit prices held for this vendor come from a public-contracts register order confirmation. |
Sources
- https://www.3brain.com/technology/coreplate-tm-3d
- https://the-myriamed-biotech-shop.myshopify.com/collections/all
- https://www.usaspending.gov/award/CONT_AWD_68HE0B23P0114_6800_-NONE-_-NONE-
- https://www.usaspending.gov/award/CONT_AWD_68HE0B25P0211_6800_-NONE-_-NONE-
- https://smlouvy.gov.cz/smlouva/soubor/37357952/Order_confirmation.pdf
doc WW-NI-80303 · rev 2026-09-03 · research use only · prices indicative and not binding until quoted in writing